GENETICS VIRTUAL LAB – BIOL 226
Lab 7
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Drosophila Class Data Review: Gene Mapping and Hypotheses Testing

Use this module to read the lab instructions, follow the workflow guide, launch the two virtual analysis tools, and access the assignment for submission.

📘 Lab ManualRead the class-data review, linkage mapping instructions, χ² testing, and GWAS overview.🗺️ Three-Point MappingAnalyze y, w, and m class data, build a linkage map, and perform the χ² test.📊 GWAS Virtual ToolAnalyze simulated GWAS data, risk alleles, odds ratio, χ², and the Manhattan plot.📝 AssignmentOpen Assignment #7.

How students should use this module

1

Read the class-data review

Review the four-gene cross, F₁/F₂ class data, epistasis, linkage, and the connection between mapping and GWAS.

2

Organize the real cross data

Use the class tables from your lab section, combine the relevant sepia classes, and reduce the mapping data to eight classes.

3

Use Tool 1: Three-Point Mapping

Identify parental, single recombinant, and double recombinant classes; determine gene order; calculate map distances, coincidence, and interference.

4

Test the y–m hypothesis

Use the χ² function in the mapping tool to test whether yellow body and miniature wings assort independently.

5

Use Tool 2: GWAS Virtual Tool

Analyze simulated human population data, calculate allele frequencies and odds ratio, run χ², and interpret the Manhattan plot.

6

Submit the assignment

Complete Assignment #7 and submit a physical copy or scanned PDF through Canvas.

Module links

These buttons are the same resources shown in Canvas, but organized as a single Lab 7 landing page.

Suggested workflow:

1. Enter your lab section F₁ and F₂ class data.
2. Use the Three-Point Mapping tool to map y, w, and m.
3. Use the same mapping tool to test the y–m independent assortment hypothesis.
4. Use the GWAS Virtual Tool to analyze the simulated human dataset.
5. Complete and submit Assignment #7.

Lab Instructions

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Assignment #7

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